منابع مشابه
Pentoxifylline Decreases Serum Level of Adhesion Molecules in Atherosclerosis Patients
Background: Inflammation is involved in development, progression, and complications of atherosclerotic disease. Clinical studies have indicated that the level of monocyte chemoattractant protein 1 (MCP-1), IL-18, and adhesion molecules correlates with the severity of atherosclerosis and can predict future cardiovascular events. Experimental studies have shown pentoxifylline (PTX) reduces these ...
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E ven by clinical and histologic findings alone it is reasonable to suspect that the pathogenesis of certain blistering skin diseases might involve abnormalities in adhesion structures. The best defined buUous diseases in this regard are pemphigus (of which there are two basic types: vulgaris and foliaceus) and bullous pemphigoid (BP) (1-3). Histology shows that the blisters in pemphigus result...
متن کاملSoluble adhesion molecules in inflammatory and vascular diseases.
For many years the vascular endothelium was believed simply to provide a passive lining between circulating blood and extravascular tissue. It is now clear, however, that this monolayer of cells on the luminal surface of all blood vessels, provides a selective barrier that responds dynamically to various stimuli, and controls a complex series of cellular reactions and interactions. The current ...
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By using the model of acute injury caused by intrapulmonary deposition of IgG immune complexes, blocking mAb to CD11a, CD11b, L-selectin, and intercellular adhesion molecule-1 (ICAM-1) were administered either i.v. or intratracheally (i.t.). The effects of these interventions were assessed according to lung injury, lung content of myeloperoxidase (MPO), TNF-alpha, and cellular content in bronch...
متن کاملAdhesion molecules and inherited diseases of the human nervous system.
Mutations in the human genes for the adhesion molecules Po, L1, and merosin cause severe abnormalities in nervous system development. Po and merosin are required for normal myelination in the nervous system, and L1 is essential for development of major axon pathways such as the corticospinal tract and corpus callosum. While mutations that lead to a loss of the adhesive function of these molecul...
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ژورنال
عنوان ژورنال: Lung
سال: 1994
ISSN: 0341-2040,1432-1750
DOI: 10.1007/bf00164437